February 11, 2014
Science Daily/University of Cambridge
Reviewing over 20 years of neuroscience research into sex differences in brain structure, researchers have conducted the first meta-analysis of the evidence. The team performed a quantitative review of the brain imaging literature testing overall sex differences in total and regional brain volumes. They found that males on average have larger total brain volumes than women (by 8 to 13 percent). Looking more closely, the researchers found differences in volume between the sexes were located in several regions. These included parts of the limbic system, and the language system.
The results highlight an asymmetric effect of sex on the developing brain. Amber Ruigrok, who carried out the study as part of her PhD, said: "For the first time we can look across the vast literature and confirm that brain size and structure are different in males and females. We should no longer ignore sex in neuroscience research, especially when investigating psychiatric conditions that are more prevalent in either males or females."