Poor sleep quality in first, third trimesters linked to preterm births

November 2, 2011

Science Daily/American Academy of Sleep Medicine

Significant risk for preterm birth found in women reporting sleep disruptions during their first and third trimesters, even after medical risk factors and income levels were accounted for. However, it's inexpensive and uncomplicated to assess, and requires only a change in behavior to help reduce risk when intervened early enough.

A study published in the Nov. 1 issue of the journal Sleep shows a significant risk for preterm birth in women reporting sleep disruptions during their first and third trimesters. The connection remained even after medical risk factors and income levels were taken into account.

"This supports the growing evidence that poor sleep is an important risk factor for preterm birth," said Michele Okun, PhD, assistant professor of psychiatry and psychology at the University of Pittsburgh School of Medicine.

"It likely occurs in the presence of other risk factors, but sleep can be measured easily and quickly during prenatal visits. Simply by assessing a woman's sleep quality, we may be able to identify a risk early in the pregnancy, when there is time to intervene. The data suggest that beneficial outcomes may be possible through modifications in behavior," Okun said.

Sleep quality in the second trimester did not correlate with increased risk. Okun said sleep often improves modestly during this part of pregnancy, although it is unclear why. One explanation might be hormones or other biological pathways playing a role, but there is no data.

Similarly, Okun and her co-authors suggest a biological cause for the increase in preterm births with disrupted sleep. Poor sleep quality has been shown to initiate inflammation, possibly activating the processes associated with childbirth prematurely. Sleep disruption also might do this in combination with stress, a known activator of inflammation.

http://www.sciencedaily.com/releases/2011/11/111101095304.htm