Adolescence/Teens3 Larry Minikes Adolescence/Teens3 Larry Minikes

How much TV you watch as a young adult may affect midlife cognitive function

December 2, 2015

Science Daily/The JAMA Network Journals

Watching a lot of TV and having a low physical activity level as a young adult were associated with worse cognitive function 25 years later in midlife, according to an article published online by JAMA Psychiatry.

 

Few studies have investigated the association between physical activity in early adulthood and cognitive function later in life. Coupled with the increasing prevalence of sedentary or screen-based activities, such as watching television, these trends are of concern for upcoming generations of young people.

 

Tina D. Hoang, M.S.P.H., of the Northern California Institute for Research and Education at the Veterans Affairs Medical Center, San Francisco, Kristine Yaffe, M.D., of the University of California, San Francisco, and coauthors examined associations between 25-year patterns of television viewing and physical activity and midlife cognition.

 

The study of 3,247 adults (ages 18 to 30) used a questionnaire to assess television viewing and physical activity during repeated visits over 25 years. High television viewing was defined as watching TV for more than three hours per day for more than two-thirds of the visits and exercise was measured as units based on time and intensity. Cognitive function was evaluated at year 25 using three tests that assessed processing speed, executive function and verbal memory.

 

Participants with high television viewing during 25 years (353 of 3,247 or 10.9 percent) were more likely to have poor cognitive performance on some of the tests. Low physical activity during 25 years in 528 of 3,247 participants (16.3 percent) was associated with poor performance on one of the tests. The odds of poor cognitive performance were almost two times higher for adults with both high television viewing and low physical activity in 107 of 3,247 (3.3 percent) participants, according to the results.

 

The authors acknowledge a few limitations, including possible selection bias and that physical activity and TV viewing were self-reported.

 

"In this biracial cohort followed for 25 years, we found that low levels of physical activity and high levels of television viewing during young to mid-adulthood were associated with worse cognitive performance in midlife. In particular, these behaviors were associated with slower processing speed and worse executive function but not with verbal memory. Participants with the least active patterns of behavior (i.e., both low physical activity and high television viewing time) were the most likely to have poor cognitive function. ... Individuals with both low physical activity and high sedentary behavior may represent a critical target group," the study concludes.

http://www.sciencedaily.com/releases/2015/12/151202132515.htm

 

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Risk-takers are smarter

November 30, 2015

Science Daily/SINTEF

Do you often take chances and yet still land on your feet? Then you probably have a well-developed brain.

 

This surprising discovery has been made as part of a project studying the brains of young male high and low risk-takers. The tests were carried out at the University of Turku in Finland under the direction of SINTEF, using both the Functional Magnetic Resonance Imaging (fMRI) and Diffusion Tensor Imaging (DTI) techniques to measure activation-related and structural correlates of risky behaviour, respectively.

 

The aim of the project was to investigate the decision-making processes within the brains of 34 young men aged 18 or 19. Based on psychological tests, they were divided into two groups of low and high risk-takers, respectively.

 

"We expected to find that young men who spend time considering what they are going to do in a given risk situation would have more highly developed neural networks in their brains than those who make quick decisions and take chances," says SINTEF researcher and behavioural analyst Dagfinn Moe. "This has been well documented in a series of studies, but our project revealed the complete opposite," he says.

 

More superhighways among risk-seekers

 

In fact, images taken of the brains of young men during the study reveal major differences in what is called "white matter." White matter constitutes the neural network, about 160,000 kilometres in length, that transmits signals in the form of nerve impulses and is crucial to the regulation of internal communication between the different areas of the brain.

 

This network is designed to analyse and transmit information in a consistent and efficient way. This is why white matter is described as containing the brain's own "superhighways." Images from brain scans revealed that those who made quick decisions and took chances during driving simulations had significantly more white matter than those who hesitated, evaluated the situation, and opted to drive safely.

 

"This finding is interesting and will be important to the way we understand the brain's development and our learning potential linked to risk-willingness," says Moe. "This will be useful information for parents, schoolteachers, sports coaches and, not least, driving instructors when it comes to assessing high risk behaviour among young drivers," he says.

 

More active, more learning

 

He believes that the explanation lies in the fact that these young men are active and seek out challenges -- both out of curiosity and a hunger to experience learning and a sense of mastery over their environment. This stimulates their brains and so their actions display a fantastic combination of playfulness, seriousness and enjoyment.

 

"All the positive brain chemicals respond under such conditions, promoting growth factors that contribute to the development of the robust neural networks that form the basis of our physical and mental skills," says Moe. "The point here is that if you're going to take risks, you have to have the required skills. And these have to be learned. Sadly, many fail during this learning process -- with tragic consequences. So this is why we're wording our findings with a Darwinian slant -- it takes brains to take risks," he says.

 

Driving games

 

The researchers employed a driving game in which participants were awarded points according to the level of risk they were willing to take.

 

The 34 young men, aged 18 or 19, were recruited and selected from upper secondary schools in Turku in Finland. The test was laid out in the form of a simulated car journey through 20 sets of traffic lights.

 

Prior to the tests, the subjects were divided into two groups -- high risk-takers (HRT) and low risk-takers (LRT) -- on the basis of the psychological sensation-seeking scale developed by Zuckerman, and actual risk-willingness displayed by the participants during initial tests. The game behaviour was the best predictor of risk-taking.

 

The task assigned to the young men was, on encountering an amber light, to decide whether a) to stop, or b) to take a chance, run the light and complete the journey through all 20 traffic lights as quickly as possible. A decision to stop added three seconds to the time taken, and a collision six seconds. In other words, the best times would be achieved by those successfully running amber lights and avoiding collisions -- but you wouldn't know if you were going to encounter another car on the crossings.

 

All the participants tried out the game before they started the formal tests, when they were subject to an MR scan of their brains. Prior to the tests they were all assessed for and cleared of any anatomical deficiencies or mental health problems or conditions that might have influenced the cognitive functions that were going to be measured. They were all right-handed.

 

Two analyses

 

The first measurement, performed with fMRI, analysed local activation differences in the gray matter of the brain between experimental conditions. FMRI registers changes in blood oxygenation and flow occurring as a result of changes in neuronal activity. The second measurement involved a Diffusion Tensor Imaging (DTI) analysis to estimate between-group difference in white matter integrity depending particularly on the quality of the myelin sheath enclosing the nerve fibres. Myelination of neural fibers is an indicator of brain maturation related to increasing efficiency of impulse transmission. The results thus provide a picture of local neural activity at the moments when decisions are taken by individuals in the two groups, as well as between-group structural difference in the quality of the brain's signal transmission system.

 

How do risk-takers think?

 

Measurements of the moment that decision-making actually takes place are taken when the subject chooses to press either "stop" or "go."

 

Results showed that high risk-seekers didn't hesitate for long before they made their decisions. Their optimism, willingness to take a chance, and belief that they would win determined their decision. Low risk-seekers, on the other hand, found themselves in a dilemma. Should they take a chance? What would happen if they crashed? This resulted in them hesitating before they made a decision to run the amber light by pressing the "go" button. Choosing the "stop" button is the safe decision that resulted in no dilemma.

 

White matter

 

Analysis of the white matter in the two groups also revealed major differences.

 

Local differences in white matter are evident between high and low risk-takers as illustrated by the coloured areas adjacent to the prefrontal cortex, within interhemispheric tracts, and in the rear of the brain that controls vision.

 

"Daring and risk-willingness activate and challenge the brain's capacity and contribute towards learning, coping strategies and development," says Moe. "They can stimulate behaviour in the direction of higher levels of risk-taking in people already predisposed to adapt to cope optimally in such situations. "We must stop regarding daring and risk-willingness simply as undesirable and uncontrolled behaviour patterns," he says.

 

Together with the Centre for Cognitive Neuroscience at the University of Turku, Moe is currently planning a new study to investigate educational approaches directed towards both high and low risk-seekers.

 

"This project will be incorporated within the 'Mind, Brain and Education (MBE)' concept, in which knowledge about the brain is more closely integrated into our understanding of educational methods and teaching outcomes," he says.

 

"We believe that this result is a very important contribution towards our understanding of how important factors such as curiosity, daring and play are for the development of the brain, as well as our physical and mental skills," he says, referring to Fridtjof Nansen's characterisation of the phenomenon: 'A spirit of daring is deeply ingrained in our nature -- in each and every one of us. But accidents will befall those who are unprepared'.

http://www.sciencedaily.com/releases/2015/11/151130113545.htm

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Parental absence affects brain development in children

November 30, 2015

Science Daily/Radiological Society of North America

Researchers in China have found that children who have been left without direct parental care for extended periods of time show larger gray matter volumes in the brain, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

 

Throughout the world, due to political upheaval, economic necessity or other reasons, parents sometimes are compelled to travel away from home for months or years at a time, leaving their children behind.

 

In China, large numbers of workers are migrating away from their children in pursuit of better jobs. Researchers wanted to study how this migration has affected the millions of children who have been left in the care of relatives for a period of more than six months without direct parental care from their biological parents.

 

"We wanted to study the brain structure in these left-behind children," said study author Yuan Xiao, Ph.D. candidate at the Huaxi MR Research Center and the Department of Radiology at West China Hospital of Sichuan University in Chengdu, Sichuan, China. "Previous studies support the hypothesis that parental care can directly affect brain development in offspring. However, most prior work is with rather severe social deprivation, such as orphans. We looked at children who were left behind with relatives when the parents left to seek employment far from home."

 

For the study, which was led by Professor Su Lui and conducted at the Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, MRI exams from 38 left-behind girls and boys (ages 7 to 13) were compared to MRI exams from a control group of 30 girls and boys (ages 7 to 14) living with their parents. The researchers then compared the gray matter volume between the two groups and measured the intelligence quotient (IQ) of each participant to assess cognitive function.

 

The researchers found larger gray matter volumes in multiple brain regions, especially in emotional brain circuitry, in the left-behind children compared to children living with their parents. The mean value of IQ scores in left-behind children was not significantly different from that of controls, but the gray matter volume in a brain region associated with memory encoding and retrieval was negatively correlated with IQ score.

 

Since larger gray matter volume may reflect insufficient pruning and maturity of the brain, the negative correlation between the gray matter volume and IQ scores suggests that growing without parental care may delay brain development.

 

"Our study provides the first empirical evidence showing that the lack of direct parental care alters the trajectory of brain development in left-behind children," Xiao said. "Public health efforts are needed to provide additional intellectual and emotional support to children left behind by parents."

http://www.sciencedaily.com/releases/2015/11/151130084008.htm

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Researchers urge caution in prescribing commonly used drug to treat ADHD

November 25, 2015

Science Daily/Wiley

Authors of new Cochrane Review remain uncertain about effect of widely used medicine on ADHD symptoms, despite large amount of research. Some evidence of increased sleeplessness and loss of appetite leads researchers to encourage more caution in use of methylphenidate.

 

The Cochrane Library publishes one of the most comprehensive assessments to date on the benefits and harms of a widely prescribed drug used to treat Attention Deficit Hyperactivity Disorder (ADHD).

 

ADHD is one of the most commonly diagnosed childhood disorders and can continue through adolescence into adulthood. Symptoms include difficulty focusing attention and remaining "on task," excessively impulsive behaviour, and extreme hyperactivity. It is estimated to affect about 5% of children, and diagnosis is based on clinical judgement rather than objective diagnostic markers.

 

Methylphenidate, more commonly known by its brand names -- Ritalin®, Concerta®, Medikinet®, and Equasym®, amongst others -- has been used to treat ADHD for more than 50 years. A team of Cochrane researchers has carefully evaluated and summarized the findings from all of the available randomized trials of this widely used drug.

 

This new Cochrane Review includes data from 185 randomized controlled trials involving more than 12,000 children or adolescents. The studies were conducted mainly in the US, Canada, and Europe, included males and females from ages 3-18, and all compared methylphenidate with either a dummy pill or no intervention.

 

When researchers combined data from identified trials, they found that methylphenidate led to modest improvements in ADHD symptoms, general behaviour, and quality of life. Analysis of adverse effects showed that children were more likely to experience sleep problems and loss of appetite while taking methylphenidate. However, the researchers' confidence in all results was very low: it was apparent from assessing the included trials that it would have been possible for people involved in the trials to have been aware of which treatment the children were taking. In addition, the reporting of results was not complete in many of the trials, and for some analyses there was variation among trial results.

 

Based upon this information, the researchers urge clinicians to be cautious in prescribing methylphenidate, and to weigh up the benefits and risks more carefully.

 

The team of 18 researchers was led by Professor Ole Jakob Storebø, Clinical Psychologist from the Psychiatric Research Unit in Region Zealand, Denmark. He says, "This review highlights the need for long-term, large, better-quality randomized trials so that we can determine the average effect of this drug more reliably."

 

Co-author Camilla Groth MD added, "This review shows very limited quality evidence for the effects of methylphenidate on children and adolescents with ADHD. Some might benefit, but we still don't know which patients will do so. Clinicians prescribing methylphenidate must take account of the poor quality of the evidence, monitor treatment carefully, and weigh up the benefits and adverse effects."

 

Another co-author, Dr Morris Zwi, Consultant Child & Adolescent Psychiatrist added, "This evidence is important for health professionals and parents of children with ADHD. Our expectations of this treatment are probably greater than they should be, and whilst our review shows some evidence of benefit, we should bear in mind that this finding was based on very low-quality evidence. What we still need are large, well-conducted trials in order to clarify the risks versus the benefits for this widely used treatment."

 

The researchers have also urged that clinicians and families should not rush to discontinue using methylphenidate. Dr Zwi added, "If a child or young person has experienced benefits without experiencing adverse effects, then there may be good clinical grounds to continue using it. Patients and their parents should discuss any decision to stop treatment with their health professional before doing so."

http://www.sciencedaily.com/releases/2015/11/151124204325.htm

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Children who take ADHD medicines have trouble sleeping

Study addresses decades of conflicting evidence of meds' effect on sleep

November 23, 2015

Science Daily/University of Nebraska-Lincoln

Children given ADHD stimulant medications take significantly longer to fall asleep, have poorer quality sleep and sleep for shorter periods, shows new research.

 

The study addresses decades of conflicting opinions and evidence about the medications' effect on sleep.

 

In what's known as a "meta-analysis," researchers from the UNL Department of Psychology combined and analyzed the results from past studies of how ADHD medications affect sleep.

 

In a study published online by the journal Pediatrics, the Nebraska researchers found children given the medicines take significantly longer to fall asleep, have poorer quality sleep, and sleep for shorter periods.

 

"We would recommend that pediatricians frequently monitor children with ADHD who are prescribed stimulants for potential adverse effects on sleep," said Katie Kidwell, a psychology doctoral student who served as the study's lead author.

 

About 1 in 14 children and adolescents in the U.S. are diagnosed with ADHD, a chronic condition that includes attention difficulty, hyperactivity and impulsiveness. In the most common form of ADHD treatment, about 3.5 million are prescribed stimulant medications such as Ritalin and Adderall.

 

Many research articles have been written in the past 30 years on whether ADHD medications harm the ability to sleep. Some researchers have found that the drugs do interfere with sleep, particularly if taken later in the day. Others maintain the medications improve patients with ADHD's ability to sleep, by relieving symptoms and reducing resistance to bedtime. Indeed, some suggest that sleep problems are caused by the medication wearing off near bedtime, creating withdrawal symptoms.

 

"One reason we did the study is that researchers have hypothesized different effects, and there are some conflicting findings in the literature," said Timothy Nelson, an associate professor of psychology involved in the study. "This is when a meta-analysis is most useful. By aggregating and previous research in a rigorous and statistical way, we can identify the main findings that we see across all these studies. It's essentially a study of studies."

 

After screening nearly 10,000 articles, Kidwell and her colleagues reviewed 167 full texts before selecting nine studies of sufficient rigor for their analysis. Tori Van Dyk and Alyssa Lundahl, also psychology doctoral students, assisted in the effort.

 

Studies chosen for the analysis were peer-reviewed, randomized experiments. The studies did not rely on parental reports of their children's sleeping patterns, instead requiring objective measures obtained through clinical sleep studies or wristband monitors used at home.

 

The researchers found that both methylphenidate medications like Ritalin and amphetamines like Adderall cause sleep problems, without identifying differences between the two. Although they were unable to determine whether varying dosage amounts changed the effect on sleep, they found that more frequent dosages made it harder for children to fall asleep.

 

They found that drugs tend to cause more sleep problems for boys. The problems dissipate, but never completely go away, the longer children continue to take the medication.

 

"Sleep impairment is related to many cognitive, emotional and behavioral consequences, such as inattention, irritability and defiance," Kidwell said. "Sleep adverse effects could undermine the benefits of stimulant medications in some cases. Pediatricians should carefully consider dosage amounts, standard versus extended release, and dosage frequencies to minimize sleep problems while effectively treating ADHD symptoms."

 

She also recommended considering behavioral treatments, such as parental training and changes to classroom procedures and homework assignments, to reduce ADHD's negative consequences.

 

"We're not saying don't use stimulant medications to treat ADHD," Nelson said. "They are well tolerated in general and there is evidence for their effectiveness. But physicians need to weigh the pros and cons in any medication decision, and considering the potential for disrupted sleep should be part of that cost-benefit analysis with stimulants."

http://www.sciencedaily.com/releases/2015/11/151123202819.htm

 

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Association between stress levels, skin problems in college students

November 23, 2015

Science Daily/Temple University Health System

College is a stressful time in the lives of students, and a new study has found that heightened levels of psychological stress are associated with skin complaints.The study aimed to assess the relationship between perceived psychological stress and the prevalence of various skin symptoms in a large, randomly selected sample of undergraduate students.

 

The study, published by the international, peer-reviewed journal Acta Dermato-Venereologica aimed to assess the relationship between perceived psychological stress and the prevalence of various skin symptoms in a large, randomly selected sample of undergraduate students. "Previous studies have demonstrated an association between stress and skin symptoms, but those studies relied on small patient samples, did not use standardized tools, are anecdotal in nature, or focused their analyses on a single skin disease," says Gil Yosopovitch, MD, Chair of the Department of Dermatology at LKSOM, Director of the Temple Itch Center, and corresponding author of the study.

 

The questionnaire-based, cross-sectional study was conducted at Temple University during the 2014 fall semester. Five thousand undergraduate students were invited to participate in a web-based survey in which they reported their perceived psychological stress and any skin complaints. Four hundred twenty-two students were included in the final sample size.

 

Respondents were divided into groupings labeled as low stress, moderate stress and high stress. Compared to low stress subjects, the high stress group suffered significantly more often from pruritus (itchy skin); alopecia (hair loss); oily, waxy or flaky patches on the scalp; hyperhidrosis (troublesome sweating); scaly skin; onychophagia (nail biting); itchy rash on hands; and trichotillomania (hair pulling). There was no association between perceived psychological stress levels and the presence of pimples, dry/sore rash, warts and other rashes on the face.

 

Despite study limitations (e.g., low response rate, absence of physical assessment of respondents), Dr. Yosipovitch says the results are important for dermatologists who treat undergraduate-aged patients. "Our findings highlight the need for health care/dermatology providers to ask these patients about their perceived levels of psychological stress. Disease flare or exacerbation while on treatment in the setting of increased stress may not necessarily reflect treatment failure." Dr. Yosipovitch adds, "These findings further suggest that non-pharmacologic therapeutic interventions should be considered for patients presenting with both skin conditions and heightened levels of psychological stress."

http://www.sciencedaily.com/releases/2015/11/151123202212.htm

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Lead exposure impacts children's sleep

Novel finding shows that lead exposure in early childhood increase risk for sleep problems, excessive daytime sleepiness

November 12, 2015

Science Daily/University of Pennsylvania School of Nursing

Lead exposure in early childhood are associated with increased risk for sleep problems and excessive daytime sleepiness in later childhood, new research shows. This is the first longitudinal, population-based study that investigated early lead exposure to sleep problems.

 

The research is based on data from a longitudinal, cohort study -- involving more than 1400 Chinese children -- that began in 2004 investigating the influence of lead exposure in relation to the development of children and adolescents' neurocognitive, behavioral and health outcomes. Lead pollution is pervasive throughout China and other developing countries, and though rates of lead exposure are decreasing due to the phase-out of leaded gasoline and increased public awareness, its persistence presents a significant health risk to children.

 

"Little is known about the impact of heavy metals exposure on children's sleep, but the study's findings highlight that environmental toxins -- such as lead -- are important pediatric risk factors for sleep disturbance," said the study's principal investigator Jianghong Liu, PhD, FAAN, Associate Professor at Penn Nursing and a faculty member at Penn's Perelman School of Medicine. "Lead exposure is preventable and treatable, but if left unchecked can result in irreversible neurological damage."

 

This is an important advancement in identifying and understanding the contribution of lead exposure to childhood insomnia and daytime sleepiness. Sleep problems are highly prevalent in children and adolescents and are associated with many adverse health outcomes including developmental disorders and intellectual and neurocognitive problems.

 

"This study addresses an important but often neglected area of sleep science, namely, environmental factors that disrupt sleep biology and behavior in children and other vulnerable populations," said the study's senior author David Dinges, PhD, Professor and Chief of the Division of Sleep & Chronobiology in the Department of Psychiatry at Penn Medicine.

 

The sleep problems reported by the adolescents in the study include excessive daytime sleepiness, insomnia, early morning awakening, trouble initiating and maintaining sleep, and having to use sleeping pills, all of which highlight poor sleep quality. Using the data from the cohort study, 665 children's blood lead levels were assessed when they were between three and five years old, and sleep was assessed six years later, when the children were between nine and eleven years old. The children and their parents answered separate questionnaires about the children's daily sleep patterns, insomnia and the use of sleeping pills.

 

Child-reported insomnia and use of sleeping pills were two times and three times more prevalent in children with blood lead levels (BLL) greater than or equal to 10 ug/dL than in children with BLL less than 10 ug/dL. This suggests that sleep disturbances appeared problematic enough for children to suffer from insomnia and even to use sleeping aids/pills in an attempt to ameliorate their symptoms.

 

"Insufficient sleep and daytime sleepiness is very prevalent in children and adolescents, and it is a pervasive problem that is linked with a significant public health burden," explained Liu. "More research needs to be done to identify contributing factors and ways to prevent or reduce their impact. Doing this can not only help alleviate sleep disturbance, but can also indirectly improve sleep-related health outcomes, including cognition, emotion, behavior, and in some cases, diabetes."

http://www.sciencedaily.com/releases/2015/11/151112161427.htm

 

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Grow kids' brains through sport

November 11, 2015

Science Daily/Université de Montréal

Organized extracurricular sport activities for children help them develop and improve cognitive skills, such as greater concentration capacity, that can in term greatly help them in the classroom, suggests a researcher.

 

In addition to being a professor at the university's School of Psychoeducation, Pagani is also a researcher at Montreal's CHU Sainte-Justine Children's hospital. Her work focuses on childhood development and the identification of factors that impact on kids as they grow up, with a view to helping parents, teachers and organizations to prioritize positive activities and behaviours. Some of her most recent research looks specifically at the impact of team sports. "We worked with information provided by parents and teachers to compare kindergarteners' activities with their classroom engagement as they grew up," Pagani said. "By time they reached the fourth grade, kids who played structured sports were identifiably better at following instructions and remaining focused in the classroom. There is something specific to the sporting environment -- perhaps the unique sense of belonging to a team to a special group with a common goal -- that appears to help kids understand the importance of respecting the rules and honoring responsibilities."

 

Mr. Mico Delianova Licastro, the Italian National Olympic Committee's US representative and organizer of the symposium, underscored that Prof. Pagani's findings support the work his organization has been undertaking for years. "Coni is keenly aware of the need for children to start at a very early age to engage in an active life style and to participate in organized sports in and out of school when of the proper age," Delianova Licastro said. "Coni is present in several countries with large populations of citizens of Italian descent, like here in the USA, to organize for the children of our communities' all-in sports competitions, ludic events and to promote a healthy diet."

http://www.sciencedaily.com/releases/2015/11/151111092546.htm

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Can parents' stress impact the health of future generations?

November 4, 2015

Science Daily/North Dakota State University

The long-term impacts of exposure to stressors during development have been the focus of recent research. The review looks at whether the effect of stressors on parents lingers to impact the health of their offspring.

 

Studies have shown that exposure to stressors accelerates the aging process. "When parents are exposed to stressors, the lifespans of their offspring and even grand offspring are often reduced. But why this happens is not well understood," said Heidinger. The researchers' paper reviews evidence that telomeres might play an important role in the process.

 

Telomeres are highly conserved, repetitive sections of DNA at the end of chromosomes. Together with other proteins, telomeres form protective caps at chromosome ends, which function a little bit like the plastic ends called aglets on shoelaces, to protect the laces from fraying.

 

During cell division and in response to stressors, telomeres get shorter while protecting the other DNA on the chromosome. Once telomeres get too short, cells stop dividing and do not function properly, which is expected to contribute to a decline in tissue function with age.

 

"Understanding how stress in the parental generation influences the telomere dynamics of subsequent generations will be important for predicting how early adversity impacts human health and how changing environmental conditions will influence animal populations," said Haussmann.

 

The review published in Biology Letters synthesizes many human and animal studies to identify current gaps in knowledge and recommend new avenues for discovery.

 

"There is evidence in humans, other mammals, and birds that parental stress exposure has a negative impact on the telomeres of their offspring," said Heidinger. "However, these effects can vary among developmental stages, among individuals, and among tissues within individuals and we need to know more about what causes these differences."

http://www.sciencedaily.com/releases/2015/11/151104152754.htm

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Stressed parent? New research shows your children may be twice as likely to have obesity

November 4, 2015

Science Daily/Obesity Society

Prior research has shown that stress is associated with obesity in adults, and now for the first time, research suggests Latino parents who feel high levels of stress are twice as likely to have children with obesity as well. Researchers examined data from the Study of Latino Youth (SOL Youth) to determine the relationship between parental stress and child weight status in the Latino population.

 

"Obesity and chronic stress were both prevalent among this Latino population, with more than one-quarter (28%) of children ages 8-16 with obesity, and nearly one-third (29%) of their parents reporting high levels of stress," said Dr. Isasi. "This study is among the first of its kind to show that parental stress is a risk factor for childhood obesity among Latinos, and adds to the understanding of family influences on child weight status."

 

In this study, Dr. Isasi and colleagues examined data on weight and stress from children and their parents from the SOL Youth study, an ancillary study to HCHC/SOL, a large community-based cohort study of Latino individuals living in the Bronx (New York City), Chicago, Miami and San Diego. The researchers followed guidelines from the Centers for Disease Control and Prevention (CDC) to define child weight status, and assessed parental stress using the Chronic Stress Burden Scale, an eight-item measure of ongoing stressors in important life domains. Stress factors included having difficulties at work or difficulties in a relationship, among others. The researchers found that prevalence of obesity in the child increased with the number of parental stress factors, from 20% among parents who experienced no stress to 34% among parents with three or more stress factors. After adjusting the data for age, sex, place of birth and location, researchers found that parents who experienced three or more chronic stressors were twice as likely to have children with obesity than parents who experienced no stress.

 

"This research should encourage clinicians and healthcare practitioners to consider high stress levels as a warning sign for developing obesity not only in the adult patient, but also in the patient's entire family," said Margarita Teran-Garcia, MD, PhD, FTOS, At-Large Mexico Council member for The Obesity Society. "Although the study is cross-sectional, it suggests that special attention should be paid to adult patients who report experiencing high stress levels in this population, and providers are encouraged to consider behavioral counseling as one measure for obesity prevention and treatments."

 

Future research is needed to examine the causes and possible preventive strategies to address the parental stress and childhood obesity associations. Additionally, future research should explore these relationships in other populations.

 

To help providers integrate obesity treatment in their practices, The Obesity Society offers free tools as part of the Treat Obesity Seriously campaign, including a BMI pad, an office poster and a BMI-measurement wheel. Clinicians can sign up to receive these materials online.

http://www.sciencedaily.com/releases/2015/11/151104134036.htm

 

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Early life stress and adolescent depression linked to impaired development of reward circuits

October 29, 2015

Science Daily/Elsevier

Early life stress is a major risk factor for later episodes of depression. In fact, adults who are abused or neglected as children are almost twice as likely to experience depression. Scientific research into this link has revealed that the increased risk following such childhood adversity is associated with sensitization of the brain circuits involved with processing threat and driving the stress response. More recently, research has begun to demonstrate that in parallel to this stress sensitization, there may also be diminished processing of reward in the brain and associated reductions in a person's ability to experience positive emotions.

 

Scientific research into this link has revealed that the increased risk following such childhood adversity is associated with sensitization of the brain circuits involved with processing threat and driving the stress response. More recently, research has begun to demonstrate that in parallel to this stress sensitization, there may also be diminished processing of reward in the brain and associated reductions in a person's ability to experience positive emotions.

 

Researchers at Duke University and the University of Texas Health Sciences Center at San Antonio looked specifically at this second phenomenon in a longitudinal neuroimaging study of adolescents, in order to better understand how early life stress contributes to depression.

 

They recruited 106 adolescents, between the ages of 11-15, who underwent an initial magnetic resonance imaging scan, along with measurements of mood and neglect. The study participants then had a second brain scan two years later.

 

The researchers focused on the ventral striatum, a deep brain region that is important for processing rewarding experiences as well as generating positive emotions, both of which are deficient in depression.

 

"Our analyses revealed that over a two-year window during early to mid-adolescence, there was an abnormal decrease in the response of the ventral striatum to reward only in adolescents who had been exposed to emotional neglect, a relatively common form of childhood adversity where parents are persistently emotionally unresponsive and unavailable to their children," explained first author Dr. Jamie Hanson.

 

"Importantly, we further showed that this decrease in ventral striatum activity predicted the emergence of depressive symptoms during this key developmental period," he added. "Our work is consistent with other recent studies finding deficient reward processing in depression, and further underscores the importance of considering such developmental pathways in efforts to protect individuals exposed to childhood adversity from later depression."

 

This study suggests that, in some people, early life stress compromises the capacity to experience enthusiasm or pleasure. In addition, the effect of early life stress may grow over time so that people who initially appear resilient may develop problems later in life.

 

"This insight is important because it suggests a neural pathway through which early life stress may contribute to depression," said Dr. John Krystal, Editor of Biological Psychiatry. "This pathway might be targeted by neural stimulation treatments. Further, it suggests that survivors of early life trauma and their families may benefit from learning about the possibility of consequences that might appear later in life. This preparation could help lead to early intervention."

http://www.sciencedaily.com/releases/2015/10/151029102524.htm

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Singing's secret power: The Ice-breaker Effect

Singing together produces faster bonding in groups

October 27, 2015

Science Daily/University of Oxford

A study with adult learners showed groups doing singing bonded faster than others. The study looked at how people attending adult education classes grew closer over seven months. The conclusion -- singing groups bonded more quickly than creative writing or craft classes.

 

We have long known the power of a good sing-along. Now, research from the University of Oxford has shown that singing is a great ice-breaker and can get groups of people to bond together more quickly than other activities can.

 

The new study, published in the Royal Society's Open Science journal, looked at how people attending adult education classes grew closer over seven months. The conclusion -- singing groups bonded more quickly than creative writing or craft classes.

 

Dr Eiluned Pearce, from Oxford's Department of Experimental Psychology led the research. She said: 'One of the key differences between humans and other primates is that we can exist in much larger social groups. Singing is found in all human societies and can be performed to some extent by the vast majority of people. It's been suggested that singing is one of the ways in which we build social cohesion when there isn't enough time to establish one-to-one connections between everyone in a group.

 

'We wanted to explore whether there was something special about singing as a bonding behaviour or whether any group activity would build bonds between members.'

 

To test the theory, the researchers worked with charity the Workers' Educational Association (WEA), the UK's largest voluntary sector provider of adult education. The WEA set up seven courses, four in singing, two in crafts and one in creative writing. Each course, made up of weekly sessions, was run over seven months, with a break in the middle.

 

Those attending the classes were given surveys before and after individual sessions in the first month, in the third month and at the end of the seven-month course. In it, they were asked to rate how close they felt to their classmates.

 

Dr Pearce said: 'We had expected the singing classes to feel closer to each other than the other classes at the end of the seven months. However, we found something different.

 

'For every class, people felt closer to each other at the end of each two-hour session than they did at the start. At the end of the seven months, all the classes were reporting similar levels of closeness.

 

'The difference between the singers and the non-singers appeared right at the start of the study. In the first month, people in the singing classes became much closer to each other over the course of a single class than those in the other classes did. Singing broke the ice better than the other activities, getting the group together faster by giving a boost to how close classmates felt towards each other right at the start of the course.

 

'In the longer term, it appears that all group activities bring people together similar amounts. In non-singing classes ties strengthened as people talked to each other either during lessons or during breaks. But this is the first clear evidence that singing is a powerful means of bonding a whole group simultaneously.'

 

Howard Croft, WEA Project Manager, said: 'We're really pleased to have taken part in this experiment, which has shown that singing can be a great way to form close bonds with others. Feeling connected to those around you, be it friends or family, is one of the key ways to improve your wellbeing. Adult education of every kind can help improve mental health and boost self-esteem, but singing together is a uniquely communal experience that can foster better relations between people from all walks of life.'

 

The research is part of a series of studies looking at how music leads to social bonding. Co-author Dr Jacques Launay said: 'Given that music-making is an important part of all human cultures throughout history we think it probably evolved to serve some purpose. Evidence suggests that the really special thing that music does for us is encourage social bonding between whole groups of people playing and dancing together'.

 

Dr Pearce added: 'Really close relationships still depend on interactions between individuals or much smaller groups, but this study shows singing can kick start the bonding process.'

http://www.sciencedaily.com/releases/2015/10/151027213419.htm

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When it comes to children's ability to think, weight and activity level both matter

October 27, 2015

Science Daily/Medical College of Georgia at Georgia Regents University

Weight and physical activity levels are both factors in a child's ability to acquire and use knowledge, a new study finds. Children who were lean and active scored better on cognitive tests than either their lean, inactive peers or overweight, inactive children, according to the study, which provides some of the first evidence that weight, independent of physical activity, is a factor.

 

"The question this paper asks that has not been asked before is whether it is just fitness that influences children's cognition," said Dr. Catherine Davis, clinical health psychologist at the Georgia Prevention Institute at the Medical College of Georgia at Georgia Regents University. "What we found is weight and physical activity both matter."

 

Children who were lean and active scored better on cognitive tests than either their lean, inactive peers or overweight, inactive children, according to the study in the journal Pediatric Exercise Science. The study provides some of the first evidence that weight, independent of physical activity, is a factor.

 

The study looked at 45 normal-weight children age 7-11, including 24 who were active and 21 who weren't. Children were considered physically active if they participated in organized activities such as swimming, gymnastics, soccer or dance for more than an hour per week. Researchers corroborated this participation with an adult, and children self-reported their physical activity. The study also looked at 45 inactive, overweight children with very similar demographics, with exact matches on gender and race, and close matches on other relevant issues such as parents' marital status and education level and age to help ensure any differences were not strongly linked to socioeconomic status.

 

As expected, the 24 normal-weight, physically active children had a lower body mass index, or BMI, less fat and a lower resting heart rate than the overweight, inactive children.

 

When researchers used the well-verified Cognitive Assessment System, the advantages continued to hold. For example, comparing the active, healthy-weight group with the overweight, inactive children, the active group scored nine points higher for planning -- things such as figuring out and carrying out a strategy and using knowledge -- and eight points higher for their ability to pay attention.

 

Weight as an independent factor among inactive children generated an even bigger difference in the ability to pay attention, with normal-weight inactive children scoring 12 points higher. Those kinds of numbers could be the difference between a child being average in terms of his cognitive function and at the top end of the normal range, Davis said. In fact, the thinner, inactive kids scored higher on attention as well as a summary measure of cognition than their heavier peers.

 

Still, comparing inactive and active children who were all a healthy weight showed that activity alone clearly provided an edge, with the active children scoring higher in most areas of cognitive function, including 11 points higher for their ability to plan and seven points higher in attention.

 

"Activity made a difference even among normal-weight kids. That verifies that physical activity makes a difference in brain function," Davis said. The good news is that children, with the help of their families and schools, have time to make healthy lifestyle changes that will modify their weight trajectory, she said.

 

"These kids are still growing. If they can cut some of the empty calories out of their diet and pick up the pace on physical activity, they may grow into their weight," Davis said.

 

The long-time investigator of how physical activity affects overweight children was surprised that weight was an independent factor affecting cognition, acknowledging that exactly how and why is unclear. It could be excessive inflammation, hormones, both or neither, Davis said. She noted that while this study focused on weight, it's likely the amount of body fat that actually matters and overweight children in the study consistently had more fat, rather than having a higher weight because of extra muscle mass, for example.

 

Next steps include studies that also include overweight, active kids to see if heavier children derive as much benefit from physical activity as their normal-weight peers, and to learn more about how weight and physical activity relate to children's brain health.

 

Both overweight and inactivity have been independently associated with a cognitive disadvantage in children. Davis published a study in 2011 in Health Psychology that showed regular exercise improves the ability of overweight, previously inactive children to think, plan and even do math. Those who participated in 40 minutes of exercise every day after school garnered even more improvement than those who were active for about 20 minutes daily. That study also used the Cognitive Assessment System as well as functional magnetic resonance imaging, which showed those who exercised experienced increased brain activity in the prefrontal cortex -- an area associated with complex thinking, decision-making and correct social behavior. A later study comparing an after-school exercise program to an after-school sedentary program, showed better brain development in the exercise group.

http://www.sciencedaily.com/releases/2015/10/151027123906.htm

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Light exposure linked to weight gain in children

October 23, 2015

Science Daily/Queensland University of Technology

A world-first study has revealed pre-schoolers exposed to more light earlier in day tend to weigh more. She says the research suggests light exposure, artificial and natural, needs to be part of the conversation about the weight of children, along with calorie intake, decreased physical activity and sleep patterns.

 

http://images.sciencedaily.com/2015/10/151023105914_1_540x360.jpg

Ms Pattinson said it is known the timing, intensity and duration of exposure to both artificial and natural light have acute biological effects in mammals. (Stock image of normal healthy child)

Credit: © Sabphoto / Fotolia

 

Cassandra Pattinson, a PhD student and her colleagues studied 48 children aged three to five from six Brisbane childcare centres over a two week period, measuring each child's sleep, activity and light exposure along with their height and weight to calculate their BMI.

 

"We found moderate intensity light exposure earlier in the day was associated with increased body mass index (BMI) while children who received their biggest dose of light -- outdoors and indoors -- in the afternoon were slimmer," said Ms Pattinson who will present her findings at the ASA Sleep Downunder Conference in Melbourne on 23 October.

 

"Surprisingly physical activity was not associated with the body mass of the children but sleep timing and light exposure was. This is the first time light has been shown to contribute to weight in children.

 

"With an estimated 42 million children around the globe under the age of five being classified as overweight or obese, it is a significant breakthrough and a world-first.

 

"Thanks to artificial lighting, including light given off by tablets, mobile phones, night lights, and television, modern children are exposed to more environmental light than any previous generation. This increase in light exposure has paralleled global increases in obesity."

 

The research team, from QUT's Institute of Health and Biomedical Innovation, worked with the Centre for Children's Health Research

 

Ms Pattinson said it is known the timing, intensity and duration of exposure to both artificial and natural light have acute biological effects in mammals.

 

"The circadian clock -- also known as the internal body clock -- is largely driven by our exposure to light and the timing of when that happens. It impacts on sleep patterns, weight gain or loss, hormonal changes and our mood," Ms Pattinson said

 

"Recent research in adults suggests exposure to light later in the day is associated with increased body mass, but no studies had investigated these effects in young children and it turns out it has the opposite effect.

 

"While adults who take in more morning light are slimmer, pre-school children exposed to morning light tend to be heavier.

 

"Factors that impact on obesity include calorie intake, decreased physical activity, short sleep duration, and variable sleep timing. Now light can be added to the mix."

 

Ms Pattinson said the next step was to figure out how the research can be used in the fight against obesity in children.

 

"We plan to conduct further studies with pre-schoolers and also infants," she said.

 

"Animal studies have shown that timing and intensity of light exposure is critical for metabolic functioning and weight status. Our findings suggest that the same applies to us.

 

"This research suggests that exposure to different types of light at different times now needs to be part of the conversation about the weight of children."

www.sciencedaily.com/releases/2015/10/151023105914.htm

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Children in foster care three times more likely to have ADHD diagnosis

October 23, 2015

Science Daily/American Academy of Pediatrics

Researchers already knew that attention-deficit/hyperactivity disorder was the most common behavioral health diagnosis among children enrolled in Medicaid. A new study found that children in foster care were three times more likely than others to have an ADHD diagnosis.

 

Researchers at the Centers for Disease Control and Prevention (CDC) examined 2011 Medicaid outpatient and prescription drug claims from multiple states across the United States. Among their key findings:

 

More than 1 in 4 children between the ages of 2 and 17 who were in foster care had received an ADHD diagnosis, compared to about 1 in 14 of all other children in Medicaid.

Children with ADHD who were in foster care were also more likely to have another disorder, with roughly half also diagnosed with conditions such as oppositional defiant disorder, depression, or anxiety. This is compared to about 1 in 3 children with ADHD in Medicaid who were not in foster care.

 

Among children with an ADHD diagnosis, those in foster care were as likely as others to be treated with ADHD medication but were more likely to have received psychological services; About 3 out of 4 of the children with ADHD in foster care received some psychological care in 2011.

 

Lead author Melissa Danielson, MSPH, a statistician with the CDC's National Center on Birth Defects and Developmental Disabilities, said findings that children in foster care experience high rates of ADHD along with other, simultaneous behavioral disorders as compared to their peers in Medicaid shows a substantial need for medical and behavioral services within this group. The high proportion of children with ADHD in foster care who receive psychological services was promising, she said, especially since behavior therapy is recommended as the first-line treatment for preschoolers with ADHD and is preferred in conjunction with medication as treatment for school-aged children with ADHD.

 

"As we work to improve the quality of care for children with ADHD, it will be important to consider the needs of special populations, including those in foster care," Ms. Danielson said. "Working together, primary care and specialty clinicians can best support the health and long-term well-being of children with ADHD."

http://www.sciencedaily.com/releases/2015/10/151023083721.htm

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Early childhood stress affects brain's response to rewards

Study finds lingering changes in brain activity

October 19, 2015

Science Daily/Duke University

A new study has pinpointed how early childhood stress affects brain activity, related to risks for depression and other mental health problems in adulthood.

 

A Duke University-led study has pinpointed how early childhood stress affects the adult brain's response to rewards. Their findings suggest a possible pathway by which childhood stress may increase risk of depression and other mental health problems in adulthood.

 

Many studies have connected early life stress to later mental health issues for adults, but little is understood about the reasons for this connection. The new study published in the current issue of Social Cognitive and Affective Neuroscience used functional magnetic resonance imaging (fMRI) to examine the relations between early life stress and reward-related brain activity in adults.

 

Participants in the study were closely monitored beginning in kindergarten and then were scanned using brain imaging when they were adults. The participants were all part of the Fast Track Project, which in 1991 began tracking how children developed across their lives.

 

For this new study, researchers focused on the levels of stress that 72 subjects were exposed to early in development. At age 26, the study participants completed an experimental game to assess how their brains processed rewards and positive feedback. The scientists focused on reward-related activity in an area of the brain known as the ventral striatum, measured using fMRI.

 

"We found that greater levels of cumulative stress during childhood and adolescence predicted lower reward-related ventral striatum activity in adulthood," said study lead author Jamie Hanson, a postdoctoral researcher at Duke's Center for Child and Family Policy and the Duke Department of Psychology and Neuroscience.

 

Hanson and colleagues found that early stress, specifically between kindergarten and grade three, was most strongly associated with muted responses to rewards in adulthood. Previous studies have identified this type of brain activity as a marker for increased risk of depression and anxiety.

 

"In participants with the greatest levels of early stress, we saw the lowest levels of activity in the ventral striatum in response to a reward," Hanson said.

 

"We think reward-related ventral striatum activity is an important marker of mental health," Hanson explained. "Past studies have focused on the processing of threat and negative emotion after early stress. Generating positive emotions may potentially buffer some of the effects of stress."

 

The researchers say that a variety of early life stresses may affect whether children or not will grow up to be at risk for mental health problems. They add that further work in this area may lead to the development of new interventions that will help prevent negative mental health outcomes after childhood stress.

http://www.sciencedaily.com/releases/2015/10/151019110955.htm

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Poor infant sleep may predict problematic toddler behavior

Study finds frequent night wakings, broken sleep patterns are linked to trouble later on

October 8, 2015

Science Daily/American Friends of Tel Aviv University

A recent study finds a definite link between poor infant sleep and compromised attention and behavior at the toddler stage.

 

Temper tantrums and misbehavior, restlessness and inattention are the trappings of the typical toddler. But they may also be signs of developmental delays or disorders. Are infant sleep irregularities red flags for later ?

 

A study recently published in Developmental Neuropsychology finds a definite link between poor infant sleep and compromised attention and behavior at the toddler stage. The research discovered that one-year-olds who experienced fragmented sleep were more likely to have difficulties concentrating and to exhibit behavioral problems at three and four years of age.

 

The research was led by Prof. Avi Sadeh of Tel Aviv University's School of Psychological Sciences and conducted by a team that included his TAU colleagues Yael Guri and Prof. Yair Bar-Haim; Dr. Gali De Marcas of the Gordon College of Education in Haifa; and Prof. Andrea Berger and Dr. Liat Tikotzky of Ben Gurion University of the Negev.

 

A predictor of future problems

 

"Many parents feel that, after a night without enough sleep, their infants are not at their 'best.' But the real concern is whether infant sleep problems -- i.e. fragmented sleep, frequent night wakings -- indicate any future developmental problems," said Prof. Sadeh. "The fact that poor infant sleep predicts later attention and behavior irregularities has never been demonstrated before using objective measures."

 

The team assessed the sleep patterns of infants at TAU's Laboratory for Children's Sleep Disorders, where Prof. Sadeh is director. The initial study included 87 one-year-olds and their parents. They revisited the lab when the infants were three to four years old. According to the study, "Night-wakings of self-soothing infants go unnoticed by their parents. Therefore, objective infant sleep measures are required when assessing the role of sleep consolidation or sleep fragmentation and its potential impact on the developing child."

 

To accomplish this, the researchers used wristwatch-like devices to objectively determine sleep patterns at the age of one, and in the follow-up visits they used a computerized attention test, the Spatial-Stroop task, to assess attentional executive control. They also referred to parental reports to determine signs of behavioral problems.

 

The results revealed significant predictive and concomitant correlations between infant sleep and toddler attention regulation and behavior problems. The study points to significant ties between sleep quality markers (sleep percentage and number of night wakings) at one year of age and attention and behavior regulation markers two to three years later.

 

Is it genetic?

 

"We don't know what the underlying causes are for the lower sleep quality and later behavior regulation problems in these children," said Prof. Sadeh. "There may be genetic or environmental causes adversely affecting both the children's sleep and their development in other domains. Our findings, however, support the importance of early diagnosis and treatment of sleep problems in infants and young children. Early interventions for infant sleep problems, very effective in improving sleep quality, could potentially improve later attention and behavior regulation."

 

The researchers are currently exploring the underlying characteristics of children who are considered "good sleepers" at the age of nine to 18 months.

http://www.sciencedaily.com/releases/2015/10/151008142505.htm

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Battling obesity in the classroom with exercise

October 5, 2015

Science Daily/University of Michigan

There's another burst of seat-bouncing, giggling and shouting in a simulated classroom. Through a new study, researchers hope to find ways to redesign classrooms and develop a curriculum to add in two-minute exercise breaks throughout the day -- "a prescription for physical activity" -- and incorporate the additional fitness as seamlessly as possible for teachers.

 

Marcus isn't having it. "How do you call that cheating?" demands Patton, an 11-year-old cyclone of energy.

 

Patton admits it's tough to sit still. Like millions of other U.S. middle and grade school kids he gets scant exercise during school because budget and time restraints have slashed recess and lunch periods.

 

Hasson, assistant professor at the U-M School of Kinesiology, seeks to remedy that problem by studying kids like Patton in a collaborative research project called Active Classroom. Partners include the School of Public Health Momentum Center, Taubman College of Architecture and Urban Planning, and School of Education.

 

Researchers hope to find ways to redesign classrooms and develop a curriculum to add in two-minute exercise breaks throughout the day -- "a prescription for physical activity" -- and incorporate the additional fitness as seamlessly as possible for teachers.

 

Clarke Fields, 9, and Patton, are between activity breaks now, meaning they'll play games, watch television or do something else sedentary between one of the 20 activity breaks. That's 40 minutes of exercise by the end of the school day -- but still only two-thirds of the recommended 60 minutes for kids.

 

Hasson's physical activity study differs from others in that it focuses on the built and curricular environments rather than solely focusing on behaviors, nutrition and exercise.

 

Her initial findings are promising: By incorporating low-, medium- or high-intensity activity, kids may burn 100-300 more calories a day. She found they quickly refocused on school work, and none reported disliking the exercise.

 

Their enthusiasm shows. Patton and Fields snap to attention when Hasson shouts: "Ready for an activity break?"

 

They jump up and record their resting heart rates. Nicki Minaj pumps out of the computer and they're off: Two minutes of high-intensity jumping jacks, skiers, butt kicks and high-knees. Hasson, who's also a former competitive volleyball player, jumps and kicks along with them, shouting encouragement.

 

"Time!" The students, breathless and smiling, shout out heart rates and perceived exertion scores and Hasson writes them on a whiteboard.

 

After the exercise, students take a quick math test to gauge how easily they reset back to learning mode. By the end of this first study phase, researchers will also know which intensities and exercises are best for weight management, fitness, cognition and other factors that impact a child's well-being in and out of the classroom.

 

The other essential parts of the research are "playable" hallways and classrooms. Hallways could be designed with pathways or longer routes and encourage room-to-room movement or activities like hopscotch. Classes might include furniture that teachers can store or rearrange and structures such as climbing walls.

 

Patton's mother Tabia arrives during another activity break. She teaches elementary school and supports Hasson's goal but remains guarded. Climbing walls in a classroom with 30 kids? That sounds hard to manage. Still, she says she'd love to be able to do this in her classroom.

 

"When (Marcus) has to sit for long periods of time, it's hard for him to focus," Tabia Patton said, and she knows this is true for many kids.

 

Hasson understands if teachers are concerned.

 

"The kids will be an easy sell," she said.

 

Indeed, their self-reported perceived exertion is almost always much lower than their actual exertion, which means they're working a lot harder than they feel like they are. They also report enjoying the exercise days more than the sedentary days when they're instructed to use a tablet.

 

The biggest challenge will be convincing overworked teachers and pressured administrators that it's doable, Hasson says.

 

Hasson's next steps are to partner with teachers like Tabia Patton in the Ann Arbor and Ypsilanti elementary schools to pilot this project in an actual classroom with the long-term goal of implementing the project nationwide. With waistlines expanding and lifespans shortening, she says it's a public health priority.

 

"This generation of kids is expected to live two to five years less than their parents, and this problem is directly related to diet and physical inactivity," Hasson said.

http://www.sciencedaily.com/releases/2015/10/151005121703.htm

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Stress causes infants to resort to habits

September 30, 2015

Science Daily/Ruhr-Universitaet-Bochum

Under stress, people are inclined to resort to habits, rather than trying out new things. In a new article, psychologists report that this is true not only for adults, but also for infants.

 

Unfamiliar situations akin to everyday life caused an increase in the stress hormone cortisol

 

Together with their colleagues, Dr Sabine Seehagen from Bochum and Prof Dr Norbert Zmyj from Dortmund studied 26 infants at the age of 15 months who underwent a learning task. Approximately half of the infants had previously been subjected to stressful situations such as they may occur in their everyday life: a stranger sat down next to them, a dancing robot played loud music and moved around, their parents left the room for a maximum of four minutes. These events caused an increase in the stress hormone cortisol. The infants in the control group spent the same period of time playing with their parents.

 

Stressed infants hardly explored alternative behaviours

 

Then, the infants were presented with a box containing two lamps and learned that one of them emitted a red light when pressed and the other one a blue light. They were allowed to press one of the lamps as often as they liked while access to the other lamp was blocked. In the subsequent test, the infants were free to choose which lamp they wanted to play with, but now neither of them lit up. Even though the lamps did no longer work, infants in the stress group continued to press the lamp that they had got used to pressing. Children in the control group exhibited more flexible behaviour and pressed the other lamp significantly more frequently.

 

Experiment design adapted for children from adult studies

 

In adults, it has been well-documented that stress promotes habits and reduces cognitive flexibility. The team from Bochum and Dortmund adapted an experimental design used in adult studies, enabling the researchers to analyse the same effects in infants. "If infants are repeatedly exposed to stress and therefore don't try out alternative behaviours, this may have a negative impact on their knowledge acquisition," says Sabine Seehagen. "This effect should be investigated in further studies in more detail."

http://www.sciencedaily.com/releases/2015/09/150930074325.htm

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Childhood stress impacts adult health

Persistent distress, distress in childhood associated with higher risk of heart disease, diabetes

September 28, 2015

Science Daily/American College of Cardiology

A 45-year study of nearly 7,000 people born in a single week in Great Britain in 1958 found psychological distress in childhood -- even when conditions improved in adulthood -- was associated with higher risk for heart disease and diabetes later in life.

 

The study, published today in the Journal of the American College of Cardiology, looked at information related to stress and mental health collected about participants in the 1958 British Birth Cohort Study at ages 7, 11, 16, 23, 33 and 42. Researchers also collected data for nine biological indicators at age 45 using information from blood samples and blood pressure measures to create a score indicating risk for heart disease and diabetes, known as the cardiometabolic risk score, for each.

 

The study found that people with persistent distress throughout their lives had the highest cardiometabolic risk score relative to participants who reported low levels of distress throughout childhood and adulthood. Using the same comparison group, participants with high levels of distress occurring primarily in childhood, and those with high levels of distress occurring primarily in adulthood also exhibited higher cardiometabolic risk. The estimated risk for cardiometabolic disease for people with persistent distress through to middle adulthood was higher than risk commonly observed for people who are overweight in childhood.

 

After adjusting for a range of factors that might affect these associations, including medication use, socioeconomic status, and health behaviors, the researchers found the risk for people who experienced high distress levels primarily in adulthood was not different compared with those with low levels of distress over their life course. But participants who experienced high distress primarily in childhood and those with persistent distress continued to have significantly higher risk scores even after considering those other factors.

 

"This study supports growing evidence that psychological distress contributes to excess risk of cardiovascular and metabolic disease and that effects may be initiated relatively early in life," said lead author Ashley Winning, ScD, MPH, of Department of Social and Behavioral Sciences at Harvard's T.H. Chan School of Public Health.

 

"While effects of distress in early childhood on higher cardiometabolic risk in adulthood appeared to be somewhat mitigated if distress levels were lower by adulthood, they were not eradicated," the authors said. "This highlights the potentially lasting impact of childhood distress on adult physical health."

 

"It is also increasingly apparent that adversity in a child's social environment increases the likelihood of developing high levels of distress. Thus, early prevention and intervention strategies focused not only on the child but also on his or her social circumstances may be an effective way to reduce the long-lasting harmful effects of distress," Winning said.

 

In the accompanying editorial in the Journal, E. Alison Holman, PhD, FNP, of the Program of Nursing Science at University of California, Irvine, said the study indicates it may not be helpful for clinicians to focus on "managing" known cardiovascular disease risk factors like smoking, obesity, elevated cholesterol and lack of exercise without addressing underlying risk factors that affect patients.

 

"When considering our patients in this broader social context, telling them to lose weight, stop smoking, eat a better diet without addressing the underlying stress or distress that may be fueling unhealthy behaviors (and lab values) may be counter-productive," Holman said. "Indeed, by 'advising' or 'directing' our patients to change their behaviors, we undermine their trust in us and may exacerbate their distress, especially if they feel stuck or unable to make the recommended changes."

 

Holman suggests patient-centered motivational interviewing and more compassionate approaches to patient communication.

 

JACC Editor-in-Chief Valentin Fuster, MD, PhD, said, "If stress contributes to cardiovascular disease in adults, as this study finds, it is easy to extrapolate the impact that stress may cause in earlier years of life when psychological and biological stages are at such a heightened state for young people."

http://www.sciencedaily.com/releases/2015/09/150928144037.htm

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