Cannabis/Medical Marijuana, Psychoactive/Psychedelic Research
Our goal is to provide you with the latest accurate, unbiased published scientific research from reliable sources to help you make the best decisions regarding your health and wellness. You will find nearly 4,000 articles in 12 categories covering a wide variety of issues. This includes over 500 articles on cannabis, the endocannabinoid system, psychoactive, psychedelic and medical/recreational/alternative drug research.
We present in an agnostic format. The information is in chronological order from the past two decades, to the extent possible.
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Crystals of N,N¬-dimethyltryptamine (DMT) imaged with polarizing microscopy. DMT is the active ingredient in the hallucinogenic drug ayahuasca. New studies from UC Davis using a rat model show that 'microdosing' or taking small doses of a psychedelic drug that do not cause hallucinations may have beneficial effects for mental health. Credit: Lindsay Cameron and Lee Dunlap
To produce cannabinoids in yeast (Saccharomyces cerevisiae), UC Berkeley synthetic biologists first engineered yeast's native mevalonate pathway to provide a high flux of geranyl pyrophosphate (GPP) and introduced a hexanoyl-CoA biosynthetic pathway combining genes from five different bacteria. They then introduced Cannabis genes encoding the enzymes involved in olivetolic acid (OA) biosynthesis, a previously undiscovered prenyl transferase enzyme (CsPT4) and cannabinoid synthases. The synthases converted cannabigerolic acid (CBGA) to the cannabinoid acids THCA and CBDA, which, upon exposure to heat, decarboxylate to tetrahydrocannabinol (THC) and cannabidiol (CBD), respectively. Credit: Jay Keasling lab, UC Berkeley
Marijuana growing. THC appeared to impact hundreds of different genes in rats and humans, but many of the genes did have something in common -- they were associated with two of the same major cellular pathways. Credit: © watman / Fotolia
Catnip has a well known effect on, its intoxicating highs are caused by nepetalactone, a type of chemical called a terpene. Credit: John Innes Centre
Liverwort (Radula perrottetii). Credit: University of Bern/Stefan Fischer
Psilocybe cubensis, 'magic mushrooms.' Credit: © aquatarkus / Fotolia
By studying the genome of a kind of octopus not known for its friendliness toward its peers, then testing its behavioral reaction to a popular mood-altering drug called MDMA or 'ecstasy,' scientists say they have found preliminary evidence of an evolutionary link between the social behaviors of the sea creature and humans, species separated by 500 million years on the evolutionary tree. Credit: Tom Kleindinst/Marine Biological Laboratory
From left to right: Nicholas DiPatrizio, Meera Nair, and Adler Dillman. Credit: I. Pittalwala, UC Riverside.
Marijuana arrest rates were already on the decline but plummeted after Colorado and Washington authorized retail sales late in 2012. Credit: David Makin, Washington State University
This figure shows the effects of three psychedelics and one control (VEH) on cortical neurons. Credit: Ly et al.
A test of tapping speed helps app users assess their level of impairment from marijuana use. Credit: Harriet de Wit
Researchers used cultured ovarian cancer cells to investigate the anti-cancer properties of hemp extract. Credit: Annie Wang
Ayahuasca is a blend of the Psychotria Viridis bush and the stems of the Banisteriopsis Caapi vine. Credit: Rafael Guimarães dos Santos
This chart from Brenner's study shows the number of plants per watershed and location of critical habitat for steelhead trout and Chinook salmon. Credit: Image courtesy of Ithaca College
Prof. Dr. Andreas Zimmer (left) and the North Rhine-Westphalia science minister Svenja Schulze (centre) in the lab of the Institute of Molecular Psychiatry at University of Bonn. Credit: © Photo: Volker Lannert/Uni Bonn
Image created using brain imaging technology, showing changes in neural signal diversity while under the influence of LSD. Credit: Image courtesy of University of Sussex
Artistic representation of LSD (in blue) fitting into a serotonin receptor (the white ribbon). Credit: Bryan Roth
Researchers reported that psilocybin decreased clinician- and patient-rated depressed mood, anxiety and death anxiety, and increased quality of life, life meaning and optimism. Credit: © Andrea / Fotolia
Researchers looked at the effects of both THC and cannabidiol (CBD) on rats' willingness to exert cognitive effort. Credit: Image courtesy of University of British Columbia